- A Cyber Attack Against Israel Shut Down a Road — The hackers targeted the Tunnels’ camera system which put the roadway into an immediate lockdown mode, shutting it down for twenty minutes. The next day the attackers managed to break in for even longer during the heavy morning rush hour, shutting the entire system for eight hours. Because all that is digital melts into code, and code is an unsolved problem.
- Random Decision Forests (PDF) — “Due to the nature of the algorithm, most Random Decision Forest implementations provide an extraordinary amount of information about the final state of the classifier and how it derived from the training data.” (via Greg Borenstein)
- BITalino — 149 Euro microcontroller board full of physiological sensors: muscles, skin conductivity, light, acceleration, and heartbeat. A platform for healthcare hardware hacking?
- How to Be a Programmer — a braindump from a guru.
ENTRIES TAGGED "medicine"
The Internot of Things, Explainy Learning, Medical Microcontroller Board, and Coder Sutra
The Internet of Americas, Pharma Pricey, Who's Watching, and Data Mining Course
- Bradley Manning and the Two Americas (Quinn Norton) — The first America built the Internet, but the second America moved onto it. And they both think they own the place now. The best explanation you’ll find for wtf is going on.
- Staggering Cost of Inventing New Drugs (Forbes) — $5BB to develop a new drug; and subject to an inverse-Moore’s law: A 2012 article in Nature Reviews Drug Discovery says the number of drugs invented per billion dollars of R&D invested has been cut in half every nine years for half a century.
- Who’s Watching You — (Tim Bray) threat modelling. Everyone should know this.
- Data Mining with Weka — learn data mining with the popular open source Weka platform.
Spatial Verbs, Open Source Malaria, Surviving Management, and Paper-like UAV
- Operative Design — A catalogue of spatial verbs. (via Adafruit)
- Open Source Malaria — open science drug discovery.
- Surviving Being (Senior) Tech Management (Kellan Elliott-McCrea) — Perspective is the thin line between a challenging but manageable problem, and chittering balled up in the corner.
- Disposable UAVs Inspired by Paper Planes (DIY Drones) — The first design, modeled after a paper plane, is created from a cellulose sheet that has electronic circuits ink-jet printed directly onto its body. Once the circuits have been laid on the plane’s frame, the craft is exposed to a UV curing process, turning the planes body into a flexible circuit board. These circuits are then connected to the planes “avionics system”, two elevons attached to the rear of the craft, which give the UAV the ability to steer itself to its destination.
Patenting Preventing Placebos, Simulating Malaria, Pricing Experiments, and Mining Bitcoin
- Patent on Medical Trial Design to Reduce Placebo Effect — drug companies say these failures are happening not because their drugs are ineffective, but because placebos have recently become more effective in clinical trials. [...] The whole idea that placebo effect is getting in the way of producing meaningful results is repugnant, I think, to anyone with scientific training. What’s even more repugnant, however, is that Fava’s group didn’t stop with a mere paper in Psychotherapy and Psychosomatics. They went on to apply for, and obtain, U.S. patents on SPCD. (via Ben Goldacre)
- OpenMalaria (Google Code) — an open source C++ program for simulating malaria epidemiology and the impacts on that epidemiology of interventions against malaria. It is based on microsimulations of Plasmodium falciparum malaria in humans, originally developed for simulating malaria vaccines. (via Victoria Stodden)
- Pricing Experiments You Might Not Know But Can Learn From — compendium of ideas and experiments for pricing.
- Retrominer — mining Bitcoins on a NES. I’m delighted by the conceit, and noticing that Bitcoin is now sufficiently part of the zeitgeist as to feature in playful hacks.
Open Source Cancer Informatics, NPR Framework, Littery Junk, BitTorrent Sync
- Open Source Cancer Informatics Software (NCIP) — we have tackled the main recommendation that came out of our June meeting with open-source thought leaders: Keep it simple. Make barriers to entry as low as possible, and reuse available resources. Specifically, we have adopted a software license that is approved by the Open Source Initiative (OSI) and have begun to migrate the code developed under the cancer Biomedical Informatics Grid® (caBIG®) Program to a public repository. Our goal in taking these steps is to remove as many barriers as possible to community participation in the continuing development of these assets. Awesome! (via John Scott)
- NPR’s Framework for Easy Apps — their three architectural maxims: Servers are for chumps; If it doesn’t work on mobile, it doesn’t work; and Build for use. Refactor for reuse..
- Random Junk in People’s Labs (Reddit) — reminded me of the contents of my “tmp” and “Downloads” and “Documents” directories: unstructured historical crap with no expiration and no current use. (Caution: swearing in the title of the Reddit post) (via Mihalyi Csikszentmihalyi)
- Sync — BitTorrent’s alpha-level tech to “automatically sync files between computers via secure, distributed technology.” Not only is it “slick for alpha” (as one friend described), it’s bloody useful: I know at least one multimillion-dollar project built on their own homegrown implementation of this same idea. (via Jason Ryan)
Medical Data Commons, Verizon Sell You, Doctor Watson, and Weedkilling Drones
- Let’s Pool Our Medical Data (TED) — John Wilbanks (of Science Commons fame) gives a strong talk for creating an open, massive, mine-able database of data about health and genomics from many sources. Money quote: Facebook would never make a change to something as important as an advertising with a sample size as small as a Phase 3 clinical trial.
- Verizon Sells App Use, Browsing Habits, Location (CNet) — Verizon Wireless has begun selling information about its customers’ geographical locations, app usage, and Web browsing activities, a move that raises privacy questions and could brush up against federal wiretapping law. To Verizon, even when you do pay for it, you’re still the product. Carriers: they’re like graverobbing organ harvesters but without the strict ethical standards.
- IBM Watson About to Launch in Medicine (Fast Company) — This fall, after six months of teaching their treatment guidelines to Watson, the doctors at Sloan-Kettering will begin testing the IBM machine on real patients. [...] On the screen, a colorful globe spins. In a few seconds, Watson offers three possible courses of chemotherapy, charted as bars with varying levels of confidence–one choice above 90% and two above 80%. “Watson doesn’t give you the answer,” Kris says. “It gives you a range of answers.” Then it’s up to [the doctor] to make the call. (via Reddit)
- Robot Kills Weeds With 98% Accuracy — During tests, this automated system gathered over a million images as it moved through the fields. Its Computer Vision System was able to detect and segment individual plants – even those that were touching each other – with 98% accuracy.
Vannevar Bush, Topic Transparency, Ancient Maps, and Concussion Sensors
- As We May Think (Vannevar Bush) — incredibly prescient piece he wrote for The Atlantic in 1945.
- Transparency and Topic Models (YouTube) — a talk from DataGotham 2012, by Hanna Wallach. She uses latent Dirichlet allocation topic models to mine text data in declassified documents where the metadata are useless. She’s working on predicting classification durations (AWESOME!). (via Matt Biddulph)
- Slippy Map of the Ancient World — this. is. so. cool!
- Technology in the NFL — X2IMPACT’s Concussion Management System (CMS) is a great example of this trend. CMS, when combined with a digital mouth guard, also made by X2, enables coaches to see head impact data in real-time and asses concussions through monitoring the accelerometers in a players mouth guard. That data helps teams to decide whether to keep a player on the field or take them off for their own safety. Insert referee joke here.
The convergence of data, privacy and cost have created a unique opportunity to reshape health care.
Coffee Rings, Scaling Laws, Autonomous Aircraft, and Dreaming Computers
- The Coffee-Ring Effect (YouTube) — beautiful video of what happens in liquids as they evaporate, explaining why coffee stains are rings, and how to create liquids with even evaporative coating.
- The Importance of Quantitative Thinking Medicine (PDF) — scaling laws underly aging, metabolism, drug delivery, BMI, and more. Full of wow moments, like Fractals are a common feature of many complex systems ranging from river networks, earthquakes, and the internet to stock markets and cities. [...] Geometrically, the nested levels of continuous branching and crenulations inherent in fractallike structures optimise the transport of information, energy, and resources by maximising the surface areas across which these essential features of life flow within any volume. Because of their fractal nature, these effective surface areas are much larger than their apparent physical size. For example, even though the volume of our lungs is about 5–6 L, the total surface area of all the alveoli is almost the size of a tennis court and the total length of airways is about 2500 km. Even more striking is that if all the arteries, veins, and capillaries of an individual’s circulatory system were laid end to end, its total length would be about 100000 km, or nearly two and a half times around the earth.
- Autonomous Robotic Plane at MIT (YouTube) — hypnotic to watch it discover the room. A product of the Robust Robotics Group at MIT.
- Electric Sheep — hypnotic screensaver, where the sleeping computers collaborate on animations. You can vote up or down the animation on your screen, changing the global gene pool. Popular animations survive and propagate.
Personalized Medicine, Reporting on Execution, Software-Defined Radio, and Beyond Hadoop
- Personalized Leukemia Treatment (NY Times) — sequenced the tumor’s DNA, found the misbehaving gene, realized there was an existing experimental treatment to tackle that gene, and it worked. Reminds me of My Daughter’s DNA, which had its origin in the poignant story of Hugh Reinhoff sequencing his daughter’s DNA to diagnose her condition. It’s all about medical professionals now, but that’s no different from the Internet starting with geeks and moving out to the masses.
- Bullseye HD — web app which allows you to make the most of the time you spend with your team, by focusing your attention on the projects and actions that are off-track or not getting enough focus, rather than wasting precious time on status updates. (via Rowan Simpson)
- Per Vices — selling software-defined radio boards (for Linux only at the moment). (via Ars Technica)
- Post-Hadoop (GigaOm) — Google have moved beyond the basic software that Hadoop was copying. Lots of interesting points in this article, including one fundamental reality – MapReduce (and thereby Hadoop) is purpose-built for organized data processing (jobs). It is baked from the core for workflows, not ad hoc exploration.