"bio" entries

Four short links: 1 August 2012

Four short links: 1 August 2012

Chinese Hackers, Edible Sensors, Quantum Physics

  1. China Hackers Hit EU Point Man and DC (Bloomberg) — wow. The extent to which EU and US government and business computer systems have been penetrated is astonishing. Stolen information is flowing out of the networks of law firms, investment banks, oil companies, drug makers, and high technology manufacturers in such significant quantities that intelligence officials now say it could cause long-term harm to U.S. and European economies. (via Gady Epstein)
  2. Digestible Microchips (Nature) — The sand-particle sized sensor consists of a minute silicon chip containing trace amounts of magnesium and copper. When swallowed, it generates a slight voltage in response to digestive juices, which conveys a signal to the surface of a person’s skin where a patch then relays the information to a mobile phone belonging to a healthcare-provider. (via Sara Winge)
  3. Quantum Mechanics Make Simple(r) — clever way to avoid the brain pain of quantum mechanics and leap straight to the “oh!”. [N]ature is described not by probabilities (which are always nonnegative), but by numbers called amplitudes that can be positive, negative, or even complex. […] In the usual “hierarchy of sciences”—with biology at the top, then chemistry, then physics, then math—quantum mechanics sits at a level between math and physics that I don’t know a good name for. Basically, quantum mechanics is the operating system that other physical theories run on as application software (with the exception of general relativity, which hasn’t yet been successfully ported to this particular OS). (via Hacker News)
  4. Selectively De-Animating Video — SIGGRAPH talk showing how to keep some things still in a video. Check out the teaser video with samples: ZOMG. I note that Maneesh Agrawala was involved: I’m a fan of his from Line Drive maps and 3D exploded views, but his entire paper list is worth reading. Wow. (via Greg Borenstein)
Four short links: 26 July 2012

Four short links: 26 July 2012

Drone Overload, Mac MySQL Tool, Better Cancer Diagnosis Through AI, and Inconstant Identifiers

  1. Drones Over Somalia are Hazard to Air Traffic (Washington Post) — In a recently completed report, U.N. officials describe several narrowly averted disasters in which drones crashed into a refu­gee camp, flew dangerously close to a fuel dump and almost collided with a large passenger plane over Mogadishu, the capital. (via Jason Leopold)
  2. Sequel Pro — free and open source Mac app for managing MySQL databases. It’s an update of CocoaMySQL.
  3. Neural Network Improves Accuracy of Least Invasive Breast Cancer Test — nice use of technology to make lives better, for which the creator won the Google Science Fair. Oh yeah, she’s 17. (via Miss Representation)
  4. Free Harder to Find on Amazon — so much for ASINs being permanent and unchangeable. Amazon “updated” the ASINs for a bunch of Project Gutenberg books, which means they’ve lost all the reviews, purchase history, incoming links, and other juice that would have put them at the top of searches for those titles. Incompetence, malice, greed, or a purely innocent mistake? (via Glyn Moody)
Four short links: 25 July 2012

Four short links: 25 July 2012

No Augmenting Money, Cat CV, Quantified Mind, and Hackable Bio

  1. Bank of England Complains About AR Bank NotesAfter downloading the free Blippar app on iPhone or Android, customers were able to ‘blipp’ any ten-pound note in circulation by opening the app and holding their phone over the note. An animated Queen, and other members of the Royal Family, then appeared on the screen and voiced opinions on the latest football matters.
  2. Kittydar — open source computer vision library in Javascript for identifying cat faces. I am not making this up. (via Kyle McDonald
  3. Quantified Mind — battery of cognitive tests, so you can track performance over time and measure the effect of interventions (coffee, diet, exercise, whatever). (via Sara Winge)
  4. Jellyfish Made From Rat Cells (Nature) — an artificial jellyfish using silicone and muscle cells from a rat’s heart. The synthetic creature, dubbed a medusoid, looks like a flower with eight petals. When placed in an electric field, it pulses and swims exactly like its living counterpart. Very cool, but the bit that caught my eye was: the team built the medusoid as a way of understanding the “fundamental laws of muscular pumps”. It is an engineer’s approach to basic science: prove that you have identified the right principles by building something with them.
Four short links: 23 July 2012

Four short links: 23 July 2012

Drone Show, Ads, GitHub's Importance, and Crowdfunding Science

  1. Unmanned Systems North America 2012 — huge tradeshow for drones. (via Directions Magazine)
  2. On Thneeds and the Death of Display Ads (John Battelle) — the video interstitial. Once anathema to nearly every publisher on the planet, this full page unit is now standard on the New York Times, Wired, Forbes, and countless other publishing sites. And while audiences may balk at seeing a full-page video ad after clicking from a search engine or other referring agent, the fact is, skipping the ad is about as hard as turning the page in a magazine. And in magazines, full page ads work for marketers. If you’d raised a kid on AdBlocker, and then at age 15 she saw the ad-filled Internet for the first time, she’d think her browser had been taken over by malware. (via Tim Bray)
  3. The Most Important Social Network: GitHubI suspect that GitHub’s servers now contain the world’s largest corpus of commentary around intellectual production.
  4. Crowdfunded Genomics — a girl with a never-before-seen developmental disorder had her exome (the useful bits of DNA) sequenced, and a never-before-seen DNA mutation found. The money for it was raised by crowdfunding. (via Ed Yong)
Four short links: 16 July 2012

Four short links: 16 July 2012

Open Access, Emergency Social Media, A/B Testing Traps, and Post-Moore Sequencing Costs

  1. Britain To Provide Free Access to Scientific Publications (Guardian) — the Finch report is being implemented! British universities now pay around £200m a year in subscription fees to journal publishers, but under the new scheme, authors will pay “article processing charges” (APCs) to have their papers peer reviewed, edited and made freely available online. The typical APC is around £2,000 per article.
  2. Social Media in an Emergency: A Best Practice Guide — from the Wellington City Council in New Zealand, who have been learning from Christchurch earthquakes and Tauranga’s oil spill.
  3. Trustworthy Online Controlled Experiments: Five Puzzling Outcomes Explained (PDF) — Microsoft Research dug into A/B tests done on Bing and reveal some subtle truths. The statistical theory of controlled experiments is well understood, but the devil is in the details and the difference between theory and practice is greater in practice than in theory […] Generating numbers is easy; generating numbers you should trust is hard! (via Greg Linden)
  4. Data Sequencing Costs (National Human Genome Research Institute) — Cost-per-megabase and cost-per-genome are dropping faster than Moore’s Law now they’ve introduced “second generation techniques” for sequencing, aka “high-throughput sequencing” or a parallelization of the process. (via JP Rangaswami)
Four short links: 9 July 2012

Four short links: 9 July 2012

Personalized Medicine, Reporting on Execution, Software-Defined Radio, and Beyond Hadoop

  1. Personalized Leukemia Treatment (NY Times) — sequenced the tumor’s DNA, found the misbehaving gene, realized there was an existing experimental treatment to tackle that gene, and it worked. Reminds me of My Daughter’s DNA, which had its origin in the poignant story of Hugh Reinhoff sequencing his daughter’s DNA to diagnose her condition. It’s all about medical professionals now, but that’s no different from the Internet starting with geeks and moving out to the masses.
  2. Bullseye HD — web app which allows you to make the most of the time you spend with your team, by focusing your attention on the projects and actions that are off-track or not getting enough focus, rather than wasting precious time on status updates. (via Rowan Simpson)
  3. Per Vices — selling software-defined radio boards (for Linux only at the moment). (via Ars Technica)
  4. Post-Hadoop (GigaOm) — Google have moved beyond the basic software that Hadoop was copying. Lots of interesting points in this article, including one fundamental reality – MapReduce (and thereby Hadoop) is purpose-built for organized data processing (jobs). It is baked from the core for workflows, not ad hoc exploration.
Four short links: 25 June 2012

Four short links: 25 June 2012

Public Spending Links, Telemedicine Questioned, Comments Re-examined, and Informed Consent

  1. Stop Treating People Like Idiots (Tom Steinberg) — governments miss the easy opportunities to link the tradeoffs they make to the point where the impacts are felt. My argument is this: key compromises or decisions should be linked to from the points where people obtain a service, or at the points where they learn about one. If my bins are only collected once a fortnight, the reason why should be one click away from the page that describes the collection times.
  2. UK Study Finds Mixed Telemedicine BenefitsThe results, in a paper to the British Medical Journal published today, found telehealth can help patients with long-term conditions avoid emergency hospital care, and also reduce deaths. However, the estimated scale of hospital cost savings is modest and may not be sufficient to offset the cost of the technology, the report finds. Overall the evidence does not warrant full scale roll-out but more careful exploration, it says. (via Mike Pearson)
  3. Pay Attention to What Nick Denton is Doing With Comments (Nieman Lab) — Most news sites have come to treat comments as little more than a necessary evil, a kind of padded room where the third estate can vent, largely at will, and tolerated mainly as a way of generating pageviews. This exhausted consensus makes what Gawker is doing so important. Nick Denton, Gawker’s founder and publisher, Thomas Plunkett, head of technology, and the technical staff have re-designed Gawker to serve the people reading the comments, rather than the people writing them.
  4. Informed Consent Source of Confusion (Nature) — fascinating look at the downstream uses of collected bio data and the difficulty in gaining informed consent: what you might learn about yourself (do I want to know I have an 8.3% greater chance of developing Alzheimers? What would I do with that knowledge besides worry?), what others might learn about you (will my records be subpoenable?), and what others might make from the knowledge (will my data be used for someone else’s financial benefit?). (via Ed Yong)
Four short links: 21 June 2012

Four short links: 21 June 2012

Randomized Trials for Policy, Crowdfunding Equity, Safe DIYBio, and Easy Unique Experiences

  1. Test, Learn, Adapt (PDF) — UK Cabinet Office paper on randomised trials for public policy. Ben Goldacre cowrote.
  2. UK EscapeTheCity Raises GBP600k in Crowd Equity — took just eight days, using the Crowdcube platform for equity-based crowd investment.
  3. DIY Bio SOPs — CC-licensed set of standard operating procedures for a bio lab. These are the SOPs that I provided to the Irish EPA as part of my “Consent Conditions” for “Contained Use of Class 1 Genetically Modified Microorganisms”. (via Alison Marigold)
  4. Shuffling Cards — shuffle a deck of cards until it’s randomised. That order of cards probably hasn’t ever been seen before in the history of mankind.
Four short links: 18 June 2012

Four short links: 18 June 2012

Facebook Sociology, Microbiome Mapping, Attention Surplus Disorder, and Makematics

  1. What Facebook Knows (MIT Tech Review) — Analyzing the 69 billion friend connections among those 721 million people showed that the world is smaller than we thought: four intermediary friends are usually enough to introduce anyone to a random stranger. and our close friends strongly sway which information we share, but overall their impact is dwarfed by the collective influence of numerous more distant contacts—what sociologists call “weak ties.” It is our diverse collection of weak ties that most powerfully determines what information we’re exposed to.
  2. Human Microbiome Mapped (The Scientist) — the Human Microbiome Project sequenced DNA of bacterial samples collected from 242 healthy volunteers. 3.5 terabytes of data, all accessible through public databases. One fascinating finding: Although each body part is characterised by some signature microbial groups, no species was universally present across every volunteer. “One of the HMP’s original mandates was to define the core microbiome, or the bugs that everyone shares,” said Huttenhower. “It looks like there really aren’t any.”
  3. Kids Today Not Inattentive (Neuroskeptic) — There’s no evidence that children today are less attentive or more distractible than kids in the past, according to research just published by a team of Pennsylvania psychologists. (via Ed Yong)
  4. Teaching Makematics at ITP (Greg Borenstein) — Computer vision algorithms, machine learning techniques, and 3D topology are becoming vital prerequisites to doing daily work in creative fields from interactive art to generative graphics, data visualization, and digital fabrication. If they don’t grapple with these subjects themselves, artists are forced to wait for others to digest this new knowledge before they can work with it.
Four short links: 11 June 2012

Four short links: 11 June 2012

Open Source Implants, Gut Fungus, Closed Source Damage, and Microtask Framework

  1. When Code Can Kill or Cure (The Economist) — I’ve linked to the dangers of closed source devices before, but this caught my eye: “In the 1990s we developed an excellent radiation-therapy treatment-planning system and tried to give it away to other clinics,” says Dr Mackie. “But when we were told by the FDA that we should get our software approved, the hospital wasn’t willing to fund it.” He formed a spin-off firm specifically to get FDA approval. It took four years and cost millions of dollars. The software was subsequently sold as a traditional, closed-source product.
  2. Gut Fungus (Wired) — the microbiome of bacteria in your body is being studied, but now researchers have scoured the poop of different species and found different mycological populations in each, and linked them to diseases.
  3. Evaluating the Harm from Closed Source (Eric Raymond) — whether or not you argue with his ethics, you will appreciate the clear description of the things you’re trading off when you choose to use closed source software.
  4. PyBossaa free, open-source, platform for creating and running crowd-sourcing applications that utilise online assistance in performing tasks that require human cognition, knowledge or intelligence such as image classification, transcription, geocoding and more! (via The Open Knowledge Foundation)