- Maximum Happy Imagination (Matt Jones) — questioning the true vision of Marc Andreessen’s recent Twitter discourse on the great future that awaits us. His analogies run out in the 20th century when it comes to the political, social and economic implications of his maximum happy imagination.
- The Mirrortocracy — It’s astonishing how many of the people conducting interviews and passing judgement on the careers of candidates have had no training at all on how to do it well. Aside from their own interviews, they may not have ever seen one. I’m all for learning on your own but at least when you write a program wrong it breaks. Without a natural feedback loop, interviewing mostly runs on myth and survivor bias.
- Longitude Prize — six prize areas, Grand Challenge style, in clean flight, antibiotic resistance, dementia, food, water, and overcoming paralysis. Mysteriously none for library system that avoids DLL hell.
- The Re-Emergence of Datalog — Michael Fogus overviews Datalog and provides examples of how it is implemented and used in Datomic, Cascalog, and the Bacwn Clojure library. See also notes from the talk.
Definitive answers require further testing
The following is from the second issue of BioCoder, the quarterly newsletter for synthetic biologists, DIY biologists, neurobiologists, and more. Download your free copy today.
Within DIYbio, one cannot escape the hacking metaphor. The metaphor is ubiquitous and, to a point, useful. The term connotes both productive play with an existing technology aimed at improvement and, at the same time, play with sinister undertones. In this sense, hacking captures the promise and pitfalls of the dual uses any mature technology might be put to, whether that technology is as dramatic as nuclear power/weapons or as mundane as a free/premium software license. But every metaphor has its limits. Pushed too far, metaphors break down, and instead of illuminating, they obscure. Which brings me to ask: how far can the hacking metaphor be pushed within DIYbio—at least the part of DIYbio falling in line with synthetic biology?